You can turn on the highlight function from the gameplay menu in any difficulty to make interactive things easier to see. I had to play around with my brightness and contrast settings with highlight turned off to spot many objects.
I just started a new game to get this, you can skip all the cutscenes just by pressing start.
All the items are on/near her desk. The toy car is on the dresser to the right and is very small so it's easy to miss. Also, to clarify the book is not the E-Book (although I think you have to read that as well) but rather, a book that is on the right side of the desk that says "Being Effective".
For all the hidden items an "X Use" pops up on the screen.