Overview:
Estimated Achievement Difficulty: 5/10
Offline: 49 (1000)
Online: None
Estimated time for 1000: 10-12 hours
Missable Achievements: 3-4 Fisherman's Foe, Handyman Carnby, Blazing Roots, If you do not replay the end of the game, and you will miss achievements if you skip sequences, you may also have small trouble with Eradication.
Glitched Achievements: None
Do Cheats Disable Achievements?: No Cheats

Introduction:
First of all go to this website.  This is a complete guide to the game that will make it a breeze.  Now I will layout what achievements you should get in each chapter of the game.

Chapter 1
You should receive 2 achievements in this chapter.  The Blind Man, do not blink during opening sequence and Blackout, complete the Chapter.

Chapter 2
Here you should receive a majority of your inventory combination achievements, shooting an explosive etc. After finding Sara in the elevator you will encounter these Ratz (they look like spider type things). Just unequip everything, switch to First Person, and press when they get close. Once you kick these 10 times achievement unlocked.  The very first humanz you encounter you will need to shoot its fissure on its body. These are the lines that glow. This will take out two achievements. You may knock out a few more inventory achievements for combining items before you get to the next section, but if you are playing through the whole game it should not be a problem.

Once you get into the parking garage, Theophile, you and Sarah will have a chat. Once the cut scene ends you will have a few achievements to knock out. Immediately take out your gun and shoot the car window in front of you and unlock the car door. Bam! achievement unlocked. Next look in the car's visor. I am 99% sure the keys will be there (if they are not then once the floor falls through there will be a car on that level and the keys in the sun visor should be there). Now try to hot wire the car, you will most likely be thrown out of the car by the Humanz, but that it is what you want. Take out your gun and an explosive bottle. Now wait until the 3 Humanz in this area are lined next to each other throw the bottle and shoot it. Bam, two more achievements one for shooting an explosive bottle and one for killing 3 Humanz at once.

Later in the level you will burn a fissure. If you are following the guide just pull out flame bullets at the right time and shoot before it gets you.
Now it is time to go down 59th street only in Cockpit View.  Just make sure when you die you press the button before .

Chapter 3
You will start off the chapter getting your PDA, immediately call everyone on it, this will still count towards your achievement even if they are unavailable.  Now follow the guide until you encounter the Vampirz; burn one to get an achievement. Then in another 2-3 minutes you should get the lighter and spray combination for burning a Humanz as well as long as you follow the guide.
Once you get to the portion with the cocoon, look for the Goldfish in the water shoot it for ten points (and yes it is an annoying little bugger!)  Now burn the cocoon for another 20 points.  Later in the chapter burn the Ratz nest for your final achievement in the chapter.

Chapter 4
Here you should get the following achievements in order if you were following the guide:
The 10 Mile Race, Purification By Fire, and Stuntman

Chapter 5
In this Chapter will get the following if you're following the guide:
Revive and Biggest of Them All.

Chapter 6
In this Chapter you will get the following achievement: Meet Again

Chapter 7
Here is where the fun begins, Burning Roots and Handyman Carnby. Both locations for Handyman Carnby contain roots. The first one in the center of the map near the lake is located lower than the area around it in a parking lot type area. Here is where you will get most of your combinations done as the items are more easily located than the others. Their will be 4 Humanz here, after you blow the door open to get inside, run into the room on the right and take Explosive Plastic bottles, but make sure to save one as you will need it. Go find the glass bottles on the right side of the building and burn the roots, then head over to the left and kill the other two Humanz. Once this is done you will get all but the Blood Pack combination and combining water with empty bottles, and those are both located in the second area in the lower left hand corner of your map.
It is kind of a mansion type building and you will have to also blow open a door to get in. The only enemy you face here is a fissure once you take the elevator up, but he cannot get you while you are in the elevator on the second floor, so make some fire bullets and shoot it. Also in the basement of this area is a knife take it once you get there and use it to fill up an empty bottle with gas once back outside the mansion.

Chapter 8
At the beginning you will discover the secret of Central Park.  Here is where you finish burning all the roots. Also if for some reason you have not killed 100 Humanz go back to Carnby Handyman location #1 and kill those four, exit the door and kill them again, repeat until you are 50 points richer as enemies should respawn once you go from location to location even if you just killed them.
Now complete the game and either shoot Sara or not, then just load up the end of Chapter 8 and done the opposite of what you just did. Congratulations on 1000!

[x360a would like to thank frank9080 for this Road Map]